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Original Article
Infection
A contact investigation after exposure to a child with disseminated tuberculosis mimicking inflammatory bowel disease
Dongsub Kim, Sodam Lee, Sang-Hee Kang, Mi-Sun Park, So-Young Yoo, Tae Yeon Jeon, Joon-Sik Choi, Bora Kim, Jong Rim Choi, Sun Young Cho, Doo Ryeon Chung, Yon Ho Choe, Yae-Jean Kim
Clin Exp Pediatr. 2018;61(11):366-370.   Published online November 15, 2018

Purpose: Tuberculosis (TB) is one of the most important diseases that cause significant mortality and morbidity in young children. Data on TB transmission from an infected child are limited. Herein, we report a case of disseminated TB in a child and conducted a contact investigation among exposed individuals. Methods: A 4-year-old child without Bacille Calmette-Guérin vaccination was diagnosed as having culture-proven...
Nephrology (Genitourinary)
Renal involvement in children and adolescents with inflammatory bowel disease
Hea Min Jang, Hee Sun Baek, Jung-Eun Kim, Ju Young Kim, Yeon Hee Lee, Hee Yeon Cho, Yon Ho Choe, Ben Kang, Byung-Ho Choe, Bong Seok Choi, Min Hyun Cho
Clin Exp Pediatr. 2018;61(10):327-331.   Published online September 12, 2018

Purpose: The incidence of inflammatory bowel disease (IBD) is rapidly increasing, and several reports have described the renal complications of IBD. We sought to evaluate the clinical manifestations of renal complications in children with IBD in order to enable early detection and prompt treatment of the complications. Methods: We retrospectively reviewed the medical records of 456 children and adolescents aged <20...
Case Report
Neurology
Complete occlusion of the right middle cerebral artery associated with Mycoplasma pneumoniae pneumonia
Ben Kang, Dong Hyun Kim, Young Jin Hong, Byong Kwan Son, Myung Kwan Lim, Yon Ho Choe, Young Se Kwon
Clin Exp Pediatr. 2016;59(3):149-152.   Published online March 31, 2016

We report a case of a 5-year-old girl who developed left hemiparesis and left facial palsy, 6 days after the initiation of fever and respiratory symptoms due to pneumonia. Chest radiography, conducted upon admission, showed pneumonic infiltration and pleural effusion in the left lung field. Brain magnetic resonance imaging showed acute ischemic infarction in the right middle cerebral artery territory....

Stroke after percutaneous transhepatic variceal obliteration of esophageal varix in Caroli syndrome
Yoo Min Lee, Yoon Lee, Yon Ho Choe
Clin Exp Pediatr. 2013;56(11):500-504.   Published online November 27, 2013

Here we present the case of an 11-year-old female patient diagnosed with Caroli syndrome, who had refractory esophageal varices. The patient had a history of recurrent bleeding from esophageal varices, which was treated with endoscopic variceal ligation thrice over a period of 2 years. However, the bleeding was not controlled. When the patient finally visited the Emergency Department, the hemoglobin...

An unusual cause of duodenal perforation due to a lollipop stick
Mi Jin Kim, Jeong Meen Seo, Yoon Lee, Yoo Min Lee, Yon Ho Choe
Clin Exp Pediatr. 2013;56(4):182-185.   Published online April 22, 2013

Children have a natural tendency to explore objects with their mouths; this can result in the swallowing of foreign objects. Most ingested foreign bodies pass uneventfully through the gastrointestinal tract. However, some foreign bodies cause obstruction or perforation of the gastrointestinal tract, requiring surgical intervention. Perforation of the gastrointestinal tract may be associated with considerable morbidity and mortality. The most...

Review Article
Change in the treatment strategy for pediatric Crohn's disease
Mi Jin Kim, Yon Ho Choe
Clin Exp Pediatr. 2010;53(9):830-833.   Published online September 13, 2010

Crohn's disease is characterized by chronic inflammation involving any portion of the gastrointestinal tract. Treating Crohn's disease is a major challenge for clinicians, as no curative therapy currently exists. Pediatric Crohn's disease is characterized by frequent relapses, a wide extent of disease, a high prevalence of extraintestinal manifestations, and a severe clinical course. The classic therapeutic approach is known as...

Clinical Lecture
Helicobacter pylori Infection in Children : Recommendations for Diagnosis and Treatment
Yon Ho Choe
Clin Exp Pediatr. 2004;47(3):235-239.   Published online March 15, 2004
Helicobacter pylori(H. pylori) infection is mainly acquired in childhood. The prevalence of infection is still highest in children in the developing world. There has been a need for clinical guidelines for H. pylori infection in children. Therefore, the North American Society for Pediatric Gastroenterology and Nutrition and the European Paediatric Task Force on H. pylori achieved consensus and developed clinical...
Case Report
A Case of Menetrier's Disease Associated with Cytomegalovirus Infection
Ju Rae Cho, Sung Kil Kang, Yun Hee Kim, Yon Ho Choe
Clin Exp Pediatr. 2001;44(10):1197-1200.   Published online October 15, 2001
We report the case of a 4 year-old boy with Menetrier's disease, who was presented with edema and hypoalbuminemia. Gastroduodenal endoscopy showed the characteristic features of giant hypertrophy of the gastric rugae and large quantities of adherent gelatinous material. Histologic findings revealed foveolar hyperplasia. The presence of CMV infection was identified by serology. His symptoms resolved spontaneously, and he has...
Original Article
Nationwide Survey on Current Status of Formula Feeding in Infants
Yon Ho Choe, Kyeong Rae Moon, Jeong Wan Seo, Jae Geon Sim, Kee Whan Yoo, Byeung Ju Jeong, Young Mi Hong
Clin Exp Pediatr. 2000;43(7):878-888.   Published online July 15, 2000
Purpose : Although breast milk is considered the best source of nutrition for infants because of its superiority over powdered milk, there are circumstances when breast milk is unavailable. Committee on Nutrition of the Korean Pediatric Society conducted an investigation into the current status of formula feeding in Korea. Methods : This investigation was conducted using questionnaires produced by our committee and distributed to mothers...
Serum Leptin Concentrations in Extremely Obese Childen
Yon Ho Choe, In Young Hyun
Clin Exp Pediatr. 1999;42(8):1136-1140.   Published online August 15, 1999
Purpose : The purpose of this study is to investigate whether there is a difference in leptin concentrations between those of children of normal weight and extremely obese children. Methods : We measured serum concentrations of leptin in 70 extremely obese subjects(7 to 12 years, 20 girls and 50 boys), whose serums had been frozen at -70℃. Height, weight, obesity index,...
Serum Leptin Concentrations in Korean Children
Yon Ho Choe, Soon Ki Kim, Young Hyun
Clin Exp Pediatr. 1998;41(7):960-965.   Published online July 15, 1998
Purpose : Leptin is the product of the ob gene secreted by adipocyte. This study investigated whether leptin concentrations were elevated in obese children and the relationship between leptin concentrations and gender, and age in Korean children. Methods : We measured serum concentrations of leptin in 124 subjects(10 to 18 years, 62 girls and 62 boys). Height, weight, obesity index, and...
Complications, Apolipoproteins and Lipoprotein(a) in Severely Obese Children in Incheon, 1996
Yon Ho Choe, Yong Hoon Jun, Soon Ki Kim, Seung Kyu Han, Byong Kwan Son, Jong Weon Choi, Soo Hwan Pai
Clin Exp Pediatr. 1997;40(10):1386-1393.   Published online October 15, 1997
Purpose : This study was designed to evaluate the incidence of complication in severely obese children and to determine whether the difference of Lp(a) between severely obese children and normal control group exists. Methods : Body weight, height and obesity index were measured in 5885(M:F= 3089:2796) elementary school children. Eight eight(M:F=63:25) were selected as severely obese children. Of the 88 children, 74 agreed to venous...
Case Report
A case of Primary Sclerosing Cholangitis with Ulcerative Colitis
Jung Sue Kim, Yon Ho Choe, Chong Jai Kim, Woo Sun Kim, In-One Kim, Jeong Kee Seo
Clin Exp Pediatr. 1996;39(10):1448-1454.   Published online October 15, 1996
An association between primary sclerosing cholangitis and ulcerative colitis is well known. But, primary sclerosing cholangitis with ulerative colitis has been rarely reported in children. The prevalence of primary sclerosing cholangitis among ulcerative colitis patiens is 3% in children. Primary sclerosing cholangitis is characterised by inflammation and fibrosis of the intrahepatic and extrahepatic bile ducts. The diagnosis of primary sclerosing cholangitis based on biochemical, histologic...
Original Article
Recent Changesin Prevalence of Hepatitis B Viral Markers in Preschool Children in Seoul,1995
Yon Ho Choe, Jeong Kee Seo, Jeong Hwan Yun, Hyo Seok Lee
Clin Exp Pediatr. 1996;39(9):1254-1259.   Published online September 15, 1996
Purpose : A nationwide hepatitis B vaccination publicity campaign and program was launched in 1988 in Korea. This survey was designed to evaluate the recent changes of the positive rates of hepatitis B surface antigen and antibody in sampled preschool children living in Seoul, 1995. Methods : Study population consisted of 218 preschool children aged 2 to 5 years. Most of them had been...
Case Report
A Case of Intestinal Neuronal Dysplasia
Se Young Kim, Yon Ho Choe, Jeong Kee Seo, In One Kim, Chong Jai Kim
Clin Exp Pediatr. 1996;39(8):1151-1157.   Published online August 15, 1996
Intestinal neuronal dysplasia(IND) is a disease characterized clinically by symptoms of intestinal obstruction and pathologically by hyperplasia of the submucosal and myenteric plexuses with formation of giant ganglia. Chronic intestinal pseudo-obstruction is a clinical diagnosis, composed of myopathic form and neuropathic form, and normal intestinal histology. Intestinal neuronal dysplasia is a neuropathic form of chronic intestinal pseudo-obstruction. The clinical presentation and the course of IND...
Original Article
Studies on the Distribution of Percentiles of Skinfold Thickness and Body Mass Index among Adolescents in Seoul
Jae Sung Ko, Kang Mo Ahn, Yon Ho Choe, Eun Hwa Choi, Yong Choi, Yoon Ok An
Clin Exp Pediatr. 1996;39(6):773-779.   Published online June 15, 1996
Purpose : With development of socioeconomic status, the prevelance of adolesecnt obesity, which is a risk factor for cardiovascular disease, is increasing. Skinfold and body mass index are indirectly used measurement of obesity in clinical and epidemiologic studies. Triceps skinfold, subscapular skinfold and body mass index were measured in adolescents aged 12 to 17. Percentile values by age and sex and...
A Statistical Study on Obesity, Blood Pressure, Serum Total Cholesterol, Serum Apolipoprotein B and Urine Sodium and Potassium in Middle School Children
Yon Ho Choe, Kang Yong Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Jin Kyu Kim
Clin Exp Pediatr. 1992;35(11):1546-1558.   Published online November 15, 1992
A comparison between remission and nonremission groups of hepatitis B virus-associated membranous nephropathy in children.
Kang Yong Park, Hye Won Park, Yon Ho Choe, Tae Sun Ha, Il Soo Ha, Yong Choi, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
Clin Exp Pediatr. 1991;34(11):1512-1518.   Published online November 30, 1991
We analyzed medical records of 35 patients with Hepatitis B virus-associated Membranous Nephropathy proven by kidney biopsy at SNUCH from Jan. 1975 to Jun. 1990. Clinical presentation, laboratory and pathologic findings were compared between remission group (who are free of proteinuria and edema in current status) and nonremission group (who have either proteinuria or edema). Age at onset was younger in remission group (4.51 ±2.93...
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